2018

Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis.  Stojic L, Lun ATL. Mangei J, Mascalchi P, Quarantotti V, Barr AR, Bakal C, Marioni J, Gergely F, Odom DT. Nucleic Acids Res. 2018 Jun 1. doi: 10.1093/nar/gky437.

A comprehensive model for the proliferation-quiescence decision in response to endogenous DNA damage in human cells. Heldt FS, Barr AR, Cooper S, Bakal C, Novak B. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2532-2537. doi: 10.1073/pnas.1715345115.


2017

NucliTrack: an integrated nuclei tracking application. Cooper S, Barr AR, Glen R, Bakal C. Bioinformatics. 2017 Oct 15;33(20):3320-3322. doi: 10.1093/bioinformatics/btx404.

Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer. Asghar US, Barr AR, Cutts R, Beaney M, Babina I, Sampath D, Giltnane J, Lacap JA, Crocker JA, Youn A, Pearson A, Herrera-Abreu MT, Bakal C, Turner NC. Clin Cancer Res. 2017 Sep 15;23(18):5561-5572. doi: 10.1158/1078-0432.CCR-17-0369.

DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression. Barr AR, Cooper S, Heldt FS, Butera F, Stoy H, Mansfeld J, Novak B, Bakal C. Nat Commun. 2017 Mar 20;8:14728. doi: 10.1038/ncomms14728.


2016

A Dynamical Framework for the All-or-None G1/S Transition. Barr AR, Heldt FS, Zhang T, Bakal C, Novak B. Cell Syst. 2016 Jan 27;2(1):27-37. doi: 10.1016/j.cels.2016.01.001.

A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Chavali PL, Chandrasekaran G, Barr AR, Tatrai P, Taylor C, Papachristou EK, Woods CG, Chavali S, Gergely F.  Nat Commun. 2016 Mar 18;7:11005. doi: 10.1038/ncomms11005.


2015

A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Barr AR, Bakal C. Sci Rep. 2015 Jun 3;5:10564. doi: 10.1038/srep10564.


2013

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Yin Z, Sadok A, Sailem H, McCarthy A, Xia X, Li F, Garcia MA, Evans L, Barr AR, Perrimon N, Marshall CJ, Wong ST, Bakal C.  Nat Cell Biol. 2013 Jul;15(7):860-71. doi: 10.1038/ncb2764.


2012

Commentary: A direct look at RNAi screens. Barr AR, Bakal C. Mol Syst Biol. 2012 Apr 24;8:580. doi: 10.1038/msb.2012.14.


2011

A primary microcephaly protein complex forms a ring around parental centrioles. Sir JH, Barr AR, Nicholas AK, Carvalho OP, Khurshid M, Seasick A, Reichelt S, D'Santos C, Woods CG, Gergely F. Nat Genet. 2011 Oct 9;43(11):1147-53. doi: 10.1038/ng.971.


2010

CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response. Barr AR, Kilmartin JV, Gergely F. J Cell Biol. 2010 Apr 5;189(1):23-39. doi: 10.1083/jcb.200912163. 


2009

Book Chapter: Knock-in and knock-out: the use of reverse genetics in somatic cells to dissect mitotic pathways. Barr AR, Zyss D, Gergely F. Methods Mol Biol. 2009;545:1-19. doi: 10.1007/978-1-60327-993-2_1.


2008

MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics. Barr AR, Gergely F. Mol Cell Biol. 2008 Dec;28(23):7199-211. doi: 10.1128/MCB.01040-08.


2007

Review: Aurora-A: the maker and breaker of spindle poles. Barr AR, Gergely F. J Cell Sci. 2007 Sep 1;120(Pt 17):2987-96.